Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23204651 | 1.00 | NCF1 (0.35) | NCF1CHRM5ADRA2CACHECACNA2D1 | |
| SCHEMBL23204653 | 0.87 | NCF1 (0.39) | NCF1CHRM5ADRA2CACHECACNA2D1 | |
| SCHEMBL22906588 | 0.87 | NCF1 (0.39) | NCF1CHRM5ADRA2CACHECACNA2D1 | |
| SCHEMBL23205152 | 0.85 | NCF1 (0.32) | NCF1CHRM5ADRA2C | |
| SCHEMBL25609366 | 0.85 | NCF1 (0.32) | NCF1CHRM5ADRA2C | |
| SCHEMBL23205087 | 0.79 | NCF1 (0.36) | NCF1 | |
| SCHEMBL23205112 | 0.79 | NCF1 (0.36) | NCF1 | |
| SCHEMBL23205570 | 0.78 | HRH3 (0.34) | NCF1CHRM5ADRA2CACHECACNA2D1 | |
| SCHEMBL23205568 | 0.78 | HRH3 (0.34) | NCF1CHRM5ADRA2CACHECACNA2D1 | |
| SCHEMBL23205106 | 0.78 | NCF1 (0.33) | NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096987-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| WO-2021067606-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2021-04-08 | — | — | WO | disclosed |