Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | HTT | P42858 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | THRB | P10828 | 4/20 | 0.65 |
| ▸ | RECQL | P46063 | 4/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL29658781 | 1.00 | MAPT (0.65) | MAPTHTTMEN1LMNAKMT2A | |
| SCHEMBL29816480 | 0.98 | KMT2A (0.62) | MAPTHTTMEN1LMNAKMT2A | |
| SCHEMBL2685093 | 0.98 | KMT2A (0.62) | MAPTHTTMEN1LMNAKMT2A | |
| Bromide SCHEMBL31674705 | 0.96 | MAPT (0.60) | MAPTHTTMEN1LMNAKMT2A | |
| Iodide SCHEMBL1628062 | 0.86 | MAPT (0.49) | MAPTHTTMEN1LMNAKMT2A | |
| Iodide SCHEMBL30594274 | 0.86 | MAPT (0.49) | MAPTHTTMEN1LMNAKMT2A | |
| SCHEMBL12056746 | 0.84 | MAPT (0.46) | MAPTHTTMEN1LMNAKMT2A | |
| Iodide SCHEMBL31552581 | 0.83 | MAPT (0.52) | MAPTHTTMEN1LMNAKMT2A | |
| Iodide SCHEMBL6864478 | 0.83 | MAPT (0.52) | MAPTHTTMEN1LMNAKMT2A | |
| Bromide SCHEMBL18153296 | 0.82 | MAPT (0.45) | MAPTHTTMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656450-A | Preparation method and application of N ^ N ^ N ligand with ultraviolet-visible absorption and fluorescence luminescence characteristics | 中山大学 | 2022-06-24 | — | — | CN | claimed |
| CN-114478352-A | Self-fixing small-molecule fluorescent probe and preparation method and application thereof | 浙江工业大学 | 2022-05-13 | — | — | CN | claimed |
| CN-112294956-A | Novel metal iridium photosensitizer and preparation method and application thereof | 中山大学 | 2021-02-02 | — | — | CN | claimed |
| US-20260077067-A1 | IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS | UNIV DUNDEE (GB) | 2026-03-19 | — | — | US | disclosed |
| US-12496361-B2 | Imaging compounds for detecting or imaging senescent cells | UNIVERSITY OF DUNDEE (GB) | 2025-12-16 | — | — | US | disclosed |
| EP-4649113-A1 | IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS | University Of Dundee (GB) | 2025-11-19 | — | — | EP | disclosed |
| US-20250114483-A1 | IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS | UNIVERSITY OF DUNDEE (GB) | 2025-04-10 | — | — | US | disclosed |
| WO-2024149992-A1 | IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS | UNIVERSITY OF DUNDEE (GB) | 2024-07-18 | — | — | WO | disclosed |
| CN-114656450-A | Preparation method and application of N ^ N ^ N ligand with ultraviolet-visible absorption and fluorescence luminescence characteristics | 中山大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-114656450-A | Preparation method and application of N ^ N ^ N ligand with ultraviolet-visible absorption and fluorescence luminescence characteristics | 中山大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-114478352-A | Self-fixing small-molecule fluorescent probe and preparation method and application thereof | 浙江工业大学 | 2022-05-13 | — | — | CN | disclosed |
| EP-0898596-B1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | AMERSHAM PHARM BIOTECH UK LTD (GB) | 2001-08-29 | — | — | EP | disclosed |
| US-6140494-A | INCREASED WATER SOLUBILITY, INCREASED PHOTOSTABILITY, BRIGHTNESS AND THE POTENTIAL REDUCTION OF INTERACTIONS WITH SURROUNDINGS | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-10-31 | — | — | US | disclosed |
| EP-0898596-A1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | Amersham Pharmacia Biotech UK Limited (GB) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040104-A1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 1997-10-30 | — | — | WO | disclosed |
| EP-0086230-B1 | MEROCYANINE-CYANINE-MEROCYANINE (MCM) ELECTRICALLY PHOTOSENSITIVE COLORANTS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-01-07 | — | — | EP | disclosed |
| US-4463076-A | Merocyanine-cyanine-merocyanine (MCM) electrically photosensitive colorants for photoelectrophoretic imaging | EASTMAN KODAK COMPANY (US) | 1984-07-31 | — | — | US | disclosed |
| EP-0086230-A4 | MEROCYANINE-CYANINE-MEROCYANINE (MCM) ELECTRICALLY PHOTOSENSITIVE COLORANTS. | EASTMAN KODAK CO (US) | 1984-05-17 | — | — | EP | disclosed |
| EP-0086230-A1 | MEROCYANINE-CYANINE-MEROCYANINE (MCM) ELECTRICALLY PHOTOSENSITIVE COLORANTS. | EASTMAN KODAK CO (US) | 1983-08-24 | — | — | EP | disclosed |
| WO-1983000752-A1 | MEROCYANINE-CYANINE-MEROCYANINE (MCM) ELECTRICALLY PHOTOSENSITIVE COLORANTS | LINK, STEVEN, GEORGE | 1983-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260077067-A1 | IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS | NR0B1, NR4A3, NCOA4 | MAPT 2242/4885HTT 1136/4885MEN1 4003/4885 |
| US-12496361-B2 | Imaging compounds for detecting or imaging senescent cells | LIMS1, GLA, TP53 | MAPT 178/4885HTT 199/4885MEN1 502/4885 |
| US-20250114483-A1 | IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS | LIMS1, GLA, TP53 | MAPT 178/4885HTT 199/4885MEN1 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.