Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL31552581 | 1.00 | MAPT (0.52) | MAPTAPPMEN1KMT2ALMNA | |
| SCHEMBL6870013 | 0.98 | MAPT (0.50) | MAPTAPPMEN1KMT2ALMNA | |
| Bromide SCHEMBL15105276 | 0.97 | MAPT (0.49) | MAPTAPPMEN1KMT2ALMNA | |
| Iodide SCHEMBL21314819 | 0.94 | MAPT (0.47) | MAPTAPPMEN1KMT2ALMNA | |
| Perchlorate SCHEMBL1405533 | 0.92 | MAPT (0.46) | MAPTAPPMEN1KMT2ALMNA | |
| SCHEMBL112622 | 0.92 | MAPT (0.45) | MAPTAPPMEN1KMT2ALMNA | |
| SCHEMBL13591490 | 0.92 | MAPT (0.45) | MAPTAPPMEN1KMT2ALMNA | |
| SCHEMBL13365118 | 0.92 | MAPT (0.45) | MAPTAPPMEN1KMT2ALMNA | |
| SCHEMBL20253062 | 0.92 | MAPT (0.45) | MAPTAPPMEN1KMT2ALMNA | |
| SCHEMBL13592714 | 0.92 | MAPT (0.45) | MAPTAPPMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635090-B1 | Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL, S.A. (FR) | 2003-10-21 | — | — | US | claimed |
| US-6821708-B2 | COMPRISES 2-(3-(1,3-DIHYDRO-1,1-DIMETHYL-3(4'-METHOXY-CARBONYL)-BENZYL-2H-BENZ(E)INDOL-2-YLIDENE)-1-PROPENYL)-1,1-DIMETHYL-3-BUTYL-1H-INDOLIUM TETRACYANOQUINODIMETHANE FOR IMPROVED PHOTOSTABILITY/OXIDATION RESISTANCE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2004-11-23 | — | — | US | disclosed |
| US-6635090-B1 | Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL, S.A. (FR) | 2003-10-21 | — | — | US | disclosed |
| US-20030138729-A1 | Cyanine-TCNQ complex dye data storage media and manufacturing method thereof | NATIONAL TSING HUA UNIVERSITY (TW) | 2003-07-24 | — | — | US | disclosed |
| US-20030068577-A1 | Novel cyanine-TCNQ dye for high density data storage media | LIAO WEN-YIH (TW) | 2003-04-10 | — | — | US | disclosed |
| EP-0517050-B1 | Test-strip containing merocyanine and nitro or nitroso substituted polyhalogenated phenol-sulfonephthaleins as protein indicators | BAYER AG (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0517055-B1 | Merocyanine protein error indicators | BAYER AG (US) | 1996-09-18 | — | — | EP | disclosed |
| US-5328850-A | Merocyanine protein error indicators | MILES INC. (US) | 1994-07-12 | — | — | US | disclosed |
| US-5279790-A | Analyzing test strip | MILES INC. (US) | 1994-01-18 | — | — | US | disclosed |
| US-5264589-A | Merocyanine protein error indicators | MILES INC. (US) | 1993-11-23 | — | — | US | disclosed |
| EP-0517055-A1 | Merocyanine protein error indicators | Bayer Corporation (US) | 1992-12-09 | — | — | EP | disclosed |
| EP-0517050-A2 | Test-strip containing merocyanine and nitro or nitroso substituted polyhalogenated phenol-sulfonephthaleins as protein indicators | Bayer Corporation (US) | 1992-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030068577-A1 | Novel cyanine-TCNQ dye for high density data storage media | KCNQ2, KCNQ4, KCNQ3 | MAPT 2137/4885APP 1718/4885MEN1 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.