Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311738 | 0.90 | MDM2 (0.51) | MDM2CASP3PTPN1KMT2A | |
| SCHEMBL3590765 | 0.90 | CASP3 (0.55) | MDM2CASP3KMT2AMDM4TP53 | |
| SCHEMBL31276542 | 0.90 | CASP3 (0.55) | MDM2CASP3KMT2AMDM4TP53 | |
| SCHEMBL30055762 | 0.90 | CASP3 (0.55) | MDM2CASP3KMT2AMDM4TP53 | |
| SCHEMBL22960722 | 0.90 | CASP3 (0.55) | MDM2CASP3KMT2AMDM4TP53 | |
| SCHEMBL14332393 | 0.90 | CASP3 (0.55) | MDM2CASP3KMT2AMDM4TP53 | |
| SCHEMBL25264909 | 0.86 | MDM2 (0.62) | MDM2CASP3PTPN1MDM4TP53 | |
| SCHEMBL25657512 | 0.86 | MDM2 (0.62) | MDM2CASP3PTPN1MDM4TP53 | |
| SCHEMBL30510289 | 0.86 | MDM2 (0.62) | MDM2CASP3PTPN1MDM4TP53 | |
| SCHEMBL2310353 | 0.82 | MDM2 (0.53) | MDM2CASP3KMT2AMDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | disclosed |