Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.73 |
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12432243 | 0.88 | ALDH1A1 (0.70) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL18821707 | 0.85 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL156331 | 0.85 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL12056707 | 0.85 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL18806572 | 0.85 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL93488 | 0.85 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL12307345 | 0.85 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL18806558 | 0.85 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL11268162 | 0.83 | NPC1 (0.96) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL2682067 | 0.83 | NPC1 (0.71) | NPC1RAB9AKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067483-A1 | NUCLEOTIDE PROBES | SONY CORPORATION (JP) | 2021-04-08 | — | — | WO | disclosed |