Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | HTR2B | P41595 | 4/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20068160 | 0.77 | HTR2A (0.47) | HTR2CHTR2AHTR2BALDH1A1 | |
| SCHEMBL25058901 | 0.77 | HTR2C (0.59) | HTR2CHTR2AHTR2BKDM1ADDB1 | |
| SCHEMBL9666624 | 0.77 | HTR2C (0.51) | HTR2CHTR2AHTR2BALDH1A1SLC6A2 | |
| SCHEMBL17986437 | 0.77 | HTR2C (0.51) | HTR2CHTR2AHTR2BALDH1A1SLC6A2 | |
| SCHEMBL30014839 | 0.75 | KDM1A (0.51) | HTR2CHTR2AHTR2BKDM1AALDH1A1 | |
| SCHEMBL9442858 | 0.74 | CHRNB4 (0.38) | KDM1A | |
| SCHEMBL15254832 | 0.74 | SLC6A4 (0.39) | HTR2CHTR2BKDM1ADDB1CRBN | |
| SCHEMBL16232157 | 0.72 | HTR2C (0.46) | HTR2CHTR2AHTR2BKDM1ATSHR | |
| SCHEMBL30578779 | 0.72 | TSHR (0.45) | DDB1CRBNALDH1A1TSHRSLC6A3 | |
| SCHEMBL7094448 | 0.71 | HTR2C (0.58) | HTR2CHTR2AHTR2BKDM1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |