Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423257 | 0.85 | FFAR1 (0.52) | HTR2CHTR2AHTR2BSLC9A1KDM1A | |
| SCHEMBL14892502 | 0.85 | FFAR1 (0.52) | HTR2CHTR2AHTR2BSLC9A1KDM1A | |
| SCHEMBL6082005 | 0.78 | TSHR (0.49) | HTR2CHTR2AHTR2BTSHR | |
| SCHEMBL25058901 | 0.75 | HTR2C (0.59) | HTR2CHTR2AHTR2BKDM1ATSHR | |
| SCHEMBL31265551 | 0.73 | HTR2A (0.36) | HTR2CHTR2AHTR2BPRCPCYP3A4 | |
| SCHEMBL3421675 | 0.73 | FFAR1 (0.45) | SLC9A1FFAR1AR | |
| SCHEMBL8183655 | 0.72 | HDAC4 (0.63) | SLC9A1FFAR1HDAC4GAA | |
| SCHEMBL987381 | 0.72 | HDAC4 (0.63) | SLC9A1FFAR1HDAC4GAA | |
| SCHEMBL12431140 | 0.72 | HDAC4 (0.63) | SLC9A1FFAR1HDAC4GAA | |
| SCHEMBL452300 | 0.72 | HDAC4 (0.63) | SLC9A1FFAR1HDAC4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140336198-A1 | Amine Derivatives as Potassium Channel Blockers | MERCK PATENT GMBH (DE) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336198-A1 | Amine Derivatives as Potassium Channel Blockers | KCNA3, KCNH3, KCNK3 | HTR2C 2143/4885HTR2A 1881/4885HTR2B 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.