Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 8/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23209115 | 1.00 | DGAT1 (0.35) | DGAT1KLKB1EGFRSSTR4 | |
| SCHEMBL23208715 | 1.00 | DGAT1 (0.35) | DGAT1KLKB1EGFRSSTR4 | |
| SCHEMBL23209044 | 1.00 | DGAT1 (0.35) | DGAT1KLKB1EGFRSSTR4 | |
| SCHEMBL23209131 | 0.90 | CKS1B (0.36) | DGAT1 | |
| SCHEMBL23208999 | 0.90 | CKS1B (0.36) | DGAT1 | |
| SCHEMBL23208716 | 0.90 | CKS1B (0.36) | DGAT1 | |
| SCHEMBL23208902 | 0.82 | PTPN11 (0.36) | DGAT1KLKB1 | |
| SCHEMBL23208806 | 0.82 | PTPN11 (0.51) | — | |
| SCHEMBL23208873 | 0.82 | PTPN11 (0.51) | — | |
| SCHEMBL23208755 | 0.79 | DGAT1 (0.35) | DGAT1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210107908-A1 | PHARMACEUTICAL COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107908-A1 | PHARMACEUTICAL COMPOUNDS | MAPT, CYP3A5, SLC5A1 | DGAT1 4132/4885KLKB1 2499/4885EGFR 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.