Propene

Propene

SCHEMBL2320982

C=C(C)C(=O)OCCOP(=O)(O)O.C=CC

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.49
TSHR P16473 3/20 0.43
LPAR3 Q9UBY5 8/20 0.40
LPAR2 Q9HBW0 6/20 0.40
ALDH1A1 P00352 2/20 0.39
LPAR1 Q92633 4/20 0.35
BTN3A1 O00481 1/20 0.35
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29614442 0.93 THRB (0.55) THRBTSHRLPAR3LPAR2ALDH1A1
SCHEMBL41531 0.93 THRB (0.55) THRBTSHRLPAR3LPAR2ALDH1A1
SCHEMBL3383211 0.92 THRB (0.47) THRBTSHRLPAR3LPAR2ALDH1A1
SCHEMBL28961030 0.91 THRB (0.53) THRBTSHRLPAR3LPAR2ALDH1A1
SCHEMBL29030334 0.91 THRB (0.53) THRBTSHRLPAR3LPAR2ALDH1A1
SCHEMBL28190751 0.91 THRB (0.53) THRBTSHRLPAR3LPAR2ALDH1A1
SCHEMBL32680488 0.91 THRB (0.53) THRBTSHRLPAR3LPAR2ALDH1A1
SCHEMBL28914945 0.91 THRB (0.53) THRBTSHRLPAR3LPAR2ALDH1A1
Ethylene SCHEMBL42784 0.91 THRB (0.53) THRBTSHRLPAR3LPAR2ALDH1A1
Ammonia Solution, Strong SCHEMBL18139579 0.91 THRB (0.53) THRBTSHRLPAR3LPAR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1565504-B1 USE OF A COPOLYMER HAVING AT LEAST ONE GRAFTED ALKOXY OR HYDROXY POLYALKYLENE GLYCOL FUNCTION AS AN AGENT FOR IMPROVING OPTICAL BRIGHTENING ACTIVATION, AND PRODUCTS OBTAINED COATEX SAS (FR) 2011-08-10 EP claimed
US-20100216962-A1 METHOD FOR NEUTRALIZING A WATER-SOLUBLE ACRYLIC POLYMER BY AT LEAST ONE MONOVALENT AGENT AND AT LEAST ONE DIVALENT AGENT, AND POLYMERS OBTAINED COATEX S.A.S (FR) 2010-08-26 US disclosed