Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1588075 | 0.74 | TSHR (0.34) | ALDH1A1 | |
| SCHEMBL847951 | 0.74 | TSHR (0.34) | ALDH1A1 | |
| SCHEMBL9817562 | 0.74 | TSHR (0.34) | ALDH1A1 | |
| SCHEMBL847288 | 0.74 | TSHR (0.34) | ALDH1A1 | |
| SCHEMBL15666424 | 0.63 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL18430746 | 0.61 | — | — | |
| SCHEMBL6433750 | 0.60 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL5401853 | 0.60 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL1870221 | 0.60 | — | — | |
| SCHEMBL2990882 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928840-B1 | 1H-Pyrazole-4-carboxamides, their preparation and their use as 11-beta-hydroxysteroid dehydrogenase inhibitors | HOFFMANN LA ROCHE (CH) | 2011-08-10 | — | — | EP | claimed |