Biphenyl

Biphenyl

SCHEMBL23211153

Oc1c(O)c(O)c(O)c(O)c1O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.69
BCL2L1 Q07817 2/20 0.65
MMP3 P08254 1/20 0.65
HSD17B10 Q99714 3/20 0.58
HPGD P15428 2/20 0.58
CRHBP P24387 2/20 0.57
CRHR2 Q13324 2/20 0.57
HDAC4 P56524 2/20 0.55
HDAC2 Q92769 2/20 0.55
HDAC8 Q9BY41 2/20 0.55
HDAC6 Q9UBN7 1/20 0.55
BACE1 P56817 1/20 0.53
ALOX5 P09917 1/20 0.52
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
CA12 O43570 1/20 0.50
GLA P06280 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28098924 0.88 ALDH1A1 (0.90) ALDH1A1BCL2L1MMP3HSD17B10HPGD
Biphenyl SCHEMBL28243758 0.84 ALDH1A1 (0.82) ALDH1A1BCL2L1MMP3HSD17B10HPGD
SCHEMBL30629023 0.83 ALDH1A1 (1.00) ALDH1A1BCL2L1MMP3HSD17B10ALOX5
SCHEMBL30108088 0.83 ALDH1A1 (1.00) ALDH1A1BCL2L1MMP3HSD17B10ALOX5
Biphenyl SCHEMBL29008551 0.83 ALDH1A1 (1.00) ALDH1A1BCL2L1MMP3HSD17B10ALOX5
Biphenyl SCHEMBL28890607 0.83 ALDH1A1 (1.00) ALDH1A1BCL2L1MMP3HSD17B10ALOX5
Biphenyl SCHEMBL4002609 0.83 ALDH1A1 (1.00) ALDH1A1BCL2L1MMP3HSD17B10ALOX5
Biphenyl SCHEMBL2548048 0.83 ALDH1A1 (1.00) ALDH1A1BCL2L1MMP3HSD17B10ALOX5
Biphenyl SCHEMBL1358618 0.83 ALDH1A1 (1.00) ALDH1A1BCL2L1MMP3HSD17B10ALOX5
Biphenyl SCHEMBL164 0.83 ALDH1A1 (1.00) ALDH1A1BCL2L1MMP3HSD17B10ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155748-B2 Star polymers and methods of use for downhole fluids BAKER HUGHES OILFIELD OPERATIONS LLC (US) 2021-10-26 US claimed
WO-2021076405-A1 STAR POLYMERS AND METHODS OF USE FOR DOWNHOLE FLUIDS BAKER HUGHES OILFIELD OPERATIONS LLC (US) 2021-04-22 WO claimed
US-20210108128-A1 STAR POLYMERS AND METHODS OF USE FOR DOWNHOLE FLUIDS BAKER HUGHES OILFIELD OPERATIONS LLC (US) 2021-04-15 US claimed
US-11155748-B2 Star polymers and methods of use for downhole fluids BAKER HUGHES OILFIELD OPERATIONS LLC (US) 2021-10-26 US disclosed
WO-2021076405-A1 STAR POLYMERS AND METHODS OF USE FOR DOWNHOLE FLUIDS BAKER HUGHES OILFIELD OPERATIONS LLC (US) 2021-04-22 WO disclosed
US-20210108128-A1 STAR POLYMERS AND METHODS OF USE FOR DOWNHOLE FLUIDS BAKER HUGHES OILFIELD OPERATIONS LLC (US) 2021-04-15 US disclosed