Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.51 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23213571 | 0.82 | HIF1A (0.51) | RAB9ANPC1HIF1AEPAS1RAPGEF3 | |
| SCHEMBL26633260 | 0.76 | CNR2 (0.56) | RAB9AALDH1A1POLBNPSR1 | |
| SCHEMBL25040117 | 0.75 | SETD2 (0.61) | RAB9ANPC1HIF1AEPAS1SMN1; SMN2 | |
| SCHEMBL23239918 | 0.75 | HRH3 (0.51) | SMN1; SMN2HTTMAPK1LMNAHRH3 | |
| SCHEMBL23213610 | 0.73 | CNR2 (0.71) | RAB9A | |
| SCHEMBL22206201 | 0.73 | JAK3 (0.48) | RAB9ANPC1HIF1AEPAS1SMN1; SMN2 | |
| SCHEMBL4915419 | 0.72 | NPC1 (0.78) | RAB9ANPC1HIF1AEPAS1SMN1; SMN2 | |
| SCHEMBL29796217 | 0.72 | HRH3 (0.51) | SMN1; SMN2LMNAHRH3MAPTALDH1A1 | |
| SCHEMBL23213253 | 0.72 | HRH3 (0.51) | SMN1; SMN2LMNAHRH3MAPTALDH1A1 | |
| SCHEMBL12671529 | 0.72 | SMN1; SMN2 (0.50) | RAB9ANPC1HIF1AEPAS1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021069705-A1 | ISOINDOLINONE COMPOUNDS | MONTE ROSA THERAPEUTICS (CH) | 2021-04-15 | — | — | WO | disclosed |