Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.71 |
| ▸ | CNR1 | P21554 | 8/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26633260 | 0.87 | CNR2 (0.56) | CNR2CNR1RAB9ACYP2A13PDCD1 | |
| SCHEMBL29716283 | 0.84 | CNR2 (0.59) | CNR2CNR1RAB9ACYP2A13PDCD1 | |
| SCHEMBL23213639 | 0.84 | CNR2 (0.59) | CNR2CNR1RAB9ACYP2A13PDCD1 | |
| SCHEMBL23213618 | 0.81 | CNR2 (0.61) | CNR2CNR1RAB9A | |
| SCHEMBL23214090 | 0.77 | GSPT1 (0.53) | CNR2CNR1 | |
| SCHEMBL23239910 | 0.76 | TP53 (0.56) | CNR2CNR1CYP2A13 | |
| SCHEMBL23240235 | 0.74 | CYP2A13 (0.53) | CNR2CNR1CYP2A13 | |
| SCHEMBL23213626 | 0.73 | RAB9A (0.53) | RAB9A | |
| SCHEMBL23214237 | 0.73 | CNR1 (0.47) | CNR2CNR1RAB9A | |
| SCHEMBL29739382 | 0.73 | CNR2 (0.47) | CNR2CNR1RAB9ACYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021069705-A1 | ISOINDOLINONE COMPOUNDS | MONTE ROSA THERAPEUTICS (CH) | 2021-04-15 | — | — | WO | disclosed |