SCHEMBL2321367

SCHEMBL2321367

CC(C)CCNC(=O)Oc1ccc2nc(-c3ccc(Oc4ccccc4C(F)(F)F)cc3)[nH]c2c1

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCD O00767 3/20 0.56
CHEK2 O96017 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2315020 0.87 SCD (0.58) SCDCHEK2
SCHEMBL2363980 0.87 CHEK2 (0.57) CHEK2
SCHEMBL3651930 0.87 SCD (0.62) SCDCHEK2
SCHEMBL2321381 0.86 SCD (0.55) SCDCHEK2
SCHEMBL2321480 0.82 CHEK2 (0.62) SCDCHEK2
SCHEMBL2803574 0.82 SCD (0.54) SCDCHEK2
SCHEMBL2313477 0.82 SCD (0.59) SCDCHEK2
SCHEMBL2318557 0.81 SCD (0.81) SCDCHEK2
SCHEMBL2315450 0.81 SCD (0.81) SCDCHEK2
SCHEMBL2316895 0.79 SCD (0.56) SCDCHEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2183222-B1 AZOLORAINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICALS CONTAINING THESE COMPOUNDS, AND THE USE THEREOF SANOFI SA (FR) 2011-08-03 EP disclosed