Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 4/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314369 | 0.88 | CHEK2 (0.57) | CHEK2 | |
| SCHEMBL3651930 | 0.86 | SCD (0.62) | SCDCHEK2 | |
| SCHEMBL2321367 | 0.86 | SCD (0.56) | SCDCHEK2 | |
| SCHEMBL2321480 | 0.83 | CHEK2 (0.62) | SCDCHEK2 | |
| SCHEMBL2320264 | 0.83 | CHEK2 (0.59) | CHEK2MMP2MMP9MMP8 | |
| SCHEMBL2317165 | 0.82 | SCD (0.59) | SCDCHEK2MMP2MMP9MMP8 | |
| SCHEMBL2808586 | 0.82 | MMP2 (0.62) | SCDCHEK2MMP2MMP9MMP8 | |
| SCHEMBL2313533 | 0.81 | CHEK2 (0.54) | CHEK2 | |
| SCHEMBL2318557 | 0.80 | SCD (0.81) | SCDCHEK2 | |
| SCHEMBL2315450 | 0.80 | SCD (0.81) | SCDCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2183222-B1 | AZOLORAINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICALS CONTAINING THESE COMPOUNDS, AND THE USE THEREOF | SANOFI SA (FR) | 2011-08-03 | — | — | EP | disclosed |