⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622400 | 1.00 | — | — | |
| SCHEMBL2226753 | 0.97 | — | — | |
| SCHEMBL3175727 | 0.76 | ESR1 (0.33) | — | |
| SCHEMBL2542826 | 0.71 | — | — | |
| SCHEMBL16921915 | 0.71 | PDE10A (0.32) | — | |
| SCHEMBL4724209 | 0.71 | — | — | |
| SCHEMBL4724056 | 0.69 | HCAR3 (0.39) | — | |
| SCHEMBL4721493 | 0.68 | HCAR3 (0.37) | — | |
| SCHEMBL12076534 | 0.68 | ELANE (0.35) | — | |
| SCHEMBL16541171 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563500-B | Azlactone-functionalized substrates for conjugation of biomolecules | 罗伯特·博世有限公司 | 2023-01-24 | — | — | CN | claimed |
| EP-3464585-B1 | AZLACTONE FUNCTIONALIZED SUBSTRATES FOR CONJUGATION OF BIOMOLECULES | BOSCH GMBH ROBERT (DE) | 2020-03-11 | — | — | EP | claimed |
| CN-106460232-B | Oligonucleotide probe inversion method for in situ synthesized probe array | 生捷科技控股公司 | 2019-12-24 | — | — | CN | claimed |
| EP-3464585-A1 | AZLACTONE FUNCTIONALIZED SUBSTRATES FOR CONJUGATION OF BIOMOLECULES | Robert Bosch GmbH (DE) | 2019-04-10 | — | — | EP | claimed |
| WO-2017207298-A1 | AZLACTONE FUNCTIONALIZED SUBSTRATES FOR CONJUGATION OF BIOMOLECULES | ROBERT BOSCH GMBH (DE) | 2017-12-07 | — | — | WO | claimed |
| US-20170342211-A1 | AZLACTONE FUNCTIONALIZED SUBSTRATES FOR CONJUGATION OF BIOMOLECULES | ROBERT BOSCH GMBH (DE) | 2017-11-30 | — | — | US | claimed |
| US-20110059501-A1 | Protein Glycosylation | ISIS INNOVATION LIMITED (GB) | 2011-03-10 | — | — | US | claimed |
| EP-1871784-A2 | PROTEIN GLYCOSYLATION | ISIS INNOVATION LIMITED (GB) | 2008-01-02 | — | — | EP | claimed |
| WO-2006106348-A2 | PROTEIN GLYCOSYLATION | ISIS INNOVATION LIMITED (GB) | 2006-10-12 | — | — | WO | claimed |
| US-12528836-B2 | Dosing regimens | APELLIS PHARMACEUTICALS, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-12458695-B2 | Dosing regimens and related compositions and methods | APELLIS PHARMACEUTICALS, INC. (US) | 2025-11-04 | — | — | US | disclosed |
| US-20250282823-A1 | CELL-REACTIVE, LONG-ACTING, OR TARGETED COMPSTATIN ANALOGS AND RELATED COMPOSITIONS AND METHODS | APELLIS PHARMACEUTICALS, INC. | 2025-09-11 | — | — | US | disclosed |
| EP-4585228-A2 | DOSING REGIMENS AND RELATED COMPOSITIONS AND METHODS | Apellis Pharmaceuticals, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| US-20250179130-A1 | METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS | ON TARGET THERAPEUTICS LLC | 2025-06-05 | — | — | US | disclosed |
| WO-2006012569-A1 | POLYMERIC MATERIALS VIA CLICK CHEMISTRY | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-02-02 | — | — | WO | disclosed |
| EP-1613735-A2 | EXPANDING THE EUKARYOTIC GENETIC CODE | The Scripps Research Institute (US) | 2006-01-11 | — | — | EP | disclosed |
| WO-2005003294-A2 | UNNATURAL REACTIVE AMINO ACID GENETIC CODE ADDITIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-01-13 | — | — | WO | disclosed |
| US-20050009049-A1 | Expanding the eukaryotic genetic code | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-01-13 | — | — | US | disclosed |
| US-20040265952-A1 | protein containing a modified amino acid that carries an azido or alkynyl group for conjugation to a second molecule such as polymer, label or drug that carries an alkynyl or azido group; translation biochemistry in eukaryotic cells; gene expression inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2004-12-30 | — | — | US | disclosed |
| WO-2004094593-A2 | EXPANDING THE EUKARYOTIC GENETIC CODE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2004-11-04 | — | — | WO | disclosed |