Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23215744 | 0.88 | GPR119 (0.65) | GPR119KCNH2 | |
| SCHEMBL29843792 | 0.88 | GPR119 (0.65) | GPR119KCNH2 | |
| SCHEMBL29843831 | 0.87 | GPR119 (0.50) | GPR119KCNH2 | |
| SCHEMBL28846424 | 0.84 | GPR119 (0.40) | GPR119KCNH2KDM1A | |
| SCHEMBL28846422 | 0.84 | GPR119 (0.40) | GPR119KCNH2KDM1A | |
| SCHEMBL23226218 | 0.84 | GPR119 (0.55) | GPR119KCNH2 | |
| SCHEMBL23215907 | 0.84 | GPR119 (0.65) | GPR119KCNH2 | |
| SCHEMBL29843768 | 0.84 | GPR119 (0.65) | GPR119KCNH2 | |
| SCHEMBL23216209 | 0.83 | GPR119 (0.54) | GPR119KCNH2KDM1A | |
| SCHEMBL23215867 | 0.83 | GPR119 (0.64) | GPR119KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021071837-A1 | GPR119 AGONISTS | KALLYOPE, INC. (US) | 2021-04-15 | — | — | WO | disclosed |