Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | HPGD | P15428 | 7/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2000840 | 0.86 | SRC (0.63) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL8848474 | 0.80 | HSD17B3 (0.77) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL28160722 | 0.78 | KDM4E (0.51) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL17716551 | 0.77 | SRC (0.57) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL9054643 | 0.77 | HSD17B3 (0.67) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL180111 | 0.76 | HPGD (0.50) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL29814668 | 0.76 | HPGD (0.50) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL31281022 | 0.75 | SRC (0.52) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL26767957 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL22100633 | 0.74 | SRC (0.58) | KDM4EALDH1A1HPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1970788-A | Flow cytometry and intracellular molecular probe technology | ZHENG FANG (CN) | 2007-05-30 | — | — | CN | claimed |
| EP-1461079-B1 | HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE CLYCOPROTEIN MUTANTS AND USES THEREOF | PROGENICS PHARM INC (US) | 2011-08-10 | — | — | EP | disclosed |
| US-20050089526-A1 | Human immunodeficiency virus envelope clycoprotein mutants and uses thereof | PROGENICS PHARMACEUTICALS, INC. | 2005-04-28 | — | — | US | disclosed |
| US-20040029171-A1 | Method for carrying out a saliva analysis | 3M ESPE AG (DE) | 2004-02-12 | — | — | US | disclosed |