Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.77 |
| ▸ | ESR1 | P03372 | 5/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.61 |
| ▸ | PDE2A | O00408 | 1/20 | 0.57 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024770 | 0.87 | HSD17B3 (1.00) | HSD17B3ESR1ESR2PDE2AERAP1 | |
| SCHEMBL10789179 | 0.87 | HSD17B3 (0.62) | HSD17B3ESR1ESR2PDE2AERAP1 | |
| SCHEMBL30640528 | 0.87 | HSD17B3 (1.00) | HSD17B3ESR1ESR2PDE2AERAP1 | |
| SCHEMBL31366988 | 0.86 | HSD17B3 (1.00) | HSD17B3ESR1ESR2PDE2AERAP1 | |
| SCHEMBL591899 | 0.86 | HSD17B3 (1.00) | HSD17B3ESR1ESR2PDE2AERAP1 | |
| SCHEMBL28446883 | 0.84 | HSD17B3 (0.96) | HSD17B3ESR1ESR2PDE2AERAP1 | |
| SCHEMBL10792486 | 0.84 | HSD17B3 (0.73) | HSD17B3ESR1ESR2PDE2AKDM4E | |
| SCHEMBL31312649 | 0.83 | HSD17B3 (0.80) | HSD17B3ESR1ESR2PDE2AERAP1 | |
| SCHEMBL2321714 | 0.80 | KDM4E (0.54) | HSD17B3KDM4EGLAGAAALDH1A1 | |
| SCHEMBL10791460 | 0.80 | HSD17B3 (0.75) | HSD17B3ESR1ESR2PDE2AERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758361-A1 | POLYMERISABLE COMPOSITON AND THE USE THEREOF | Novartis AG (CH) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029959-A1 | POLYMERISABLE COMPOSITON AND THE USE THEREOF | CIBA-GEIGY AG (CH) | 1995-11-09 | — | — | WO | disclosed |
| EP-0111746-B1 | SULFONIC-ACID ESTERS OF HYDROXYCOUMARINES, THEIR PREPARATION AND MEDICINES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1987-09-16 | — | — | EP | disclosed |
| US-4618622-A | ANTIDEPRESSANTS, ANTIALLERGENS | BASF AKTIENGESELLSCHAFT (DE) | 1986-10-21 | — | — | US | disclosed |
| EP-0111746-A2 | Sulfonic-acid esters of hydroxycoumarines, their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1984-06-27 | — | — | EP | disclosed |