SCHEMBL2321720

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10088815	0.94	S1PR1 (0.39)	S1PR1S1PR4S1PR5CD274ALOX5
	SCHEMBL10088862	0.91	CD274 (0.39)	S1PR1S1PR4S1PR5CD274ALOX5
	SCHEMBL10089046	0.91	ALOX5 (0.38)	S1PR1S1PR4S1PR5CD274ALOX5
	SCHEMBL10088820	0.89	S1PR1 (0.40)	S1PR1S1PR4S1PR5CD274
	SCHEMBL10088847	0.89	CD274 (0.39)	S1PR1S1PR4S1PR5CD274ALOX5
	SCHEMBL10088883	0.89	S1PR1 (0.35)	S1PR1S1PR4S1PR5CD274ALOX5
	SCHEMBL10089051	0.89	MRGPRX4 (0.36)	S1PR1S1PR4S1PR5CD274ALOX5
	SCHEMBL10088819	0.89	S1PR1 (0.41)	S1PR1S1PR4S1PR5CD274RXRA
	SCHEMBL10088870	0.89	S1PR1 (0.37)	S1PR1S1PR4S1PR5CD274ALOX5
	SCHEMBL10088831	0.89	S1PR1 (0.45)	S1PR1S1PR4S1PR5ALOX5RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.