Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 6/20 | 0.38 |
| ▸ | WNT3A | P56704 | 6/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26476323 | 0.84 | PTPN1 (0.44) | CTNNB1WNT3A | |
| SCHEMBL5987785 | 0.82 | TTR (0.47) | CTNNB1WNT3AXDHSLC22A12TSHR | |
| SCHEMBL23217552 | 0.80 | NPC1 (0.34) | CTNNB1WNT3AKDM4EMEN1MAPT | |
| SCHEMBL30950146 | 0.78 | MAPT (0.39) | CTNNB1WNT3AXDHSLC22A12TSHR | |
| SCHEMBL18585526 | 0.78 | LCK (0.41) | XDHSLC22A12TSHRMEN1KMT2A | |
| SCHEMBL26095095 | 0.78 | MAPT (0.39) | CTNNB1WNT3AXDHSLC22A12TSHR | |
| SCHEMBL5987396 | 0.77 | NOTUM (0.44) | XDHKDM4EL3MBTL1HPGDMEN1 | |
| SCHEMBL23217544 | 0.74 | ALDH1A1 (0.46) | TSHRMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL31026070 | 0.74 | ALDH1A1 (0.46) | TSHRMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL13736985 | 0.73 | CTNNB1 (0.68) | CTNNB1WNT3AIDO1HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |