Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 20/20 | 0.58 |
| ▸ | F11 | P03951 | 9/20 | 0.42 |
| ▸ | TPSB2 | P20231 | 7/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217547 | 1.00 | CFD (0.58) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL30009740 | 0.91 | CFD (0.48) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23241532 | 0.91 | CFD (0.48) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23217682 | 0.84 | CFD (0.57) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23217681 | 0.84 | CFD (0.57) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL28943908 | 0.84 | CFD (0.53) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL28772773 | 0.82 | CFD (0.61) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL28772685 | 0.81 | CFD (0.53) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23241531 | 0.81 | CFD (0.53) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL28772753 | 0.79 | CFD (0.47) | CFDF11TPSB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |