Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CBLB | Q13191 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21201201 | 0.75 | PDK2 (0.48) | PDK2PDK4RIPK1HRH4CBLB | |
| SCHEMBL2318818 | 0.74 | RHEB (0.39) | RHEB | |
| SCHEMBL24020387 | 0.66 | HRH4 (0.56) | RHEBALDH1A1HRH4HTTL3MBTL1 | |
| SCHEMBL31424595 | 0.65 | PDK2 (0.39) | PDK2PDK4RIPK1JAK2JAK1 | |
| SCHEMBL7701684 | 0.64 | HRH4 (0.56) | KDM4EALDH1A1HRH4HSD17B10HPGD | |
| SCHEMBL31068649 | 0.64 | EGLN1 (0.45) | KDM4EALDH1A1HRH4LMNAHTT | |
| SCHEMBL6323065 | 0.62 | PIM3 (0.41) | KDM4EHTT | |
| SCHEMBL2318935 | 0.62 | EGLN1 (0.47) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL30280904 | 0.61 | PDK2 (0.41) | PDK2PDK4SLC6A3KDM4EALDH1A1 | |
| SCHEMBL7705454 | 0.61 | PIN1 (0.53) | RHEBKDM4EALDH1A1HRH4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097491-A1 | BENZIMIDAZOLE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-08-11 | — | — | WO | disclosed |