Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 19/20 | 0.67 |
| ▸ | TPSB2 | P20231 | 9/20 | 0.51 |
| ▸ | F11 | P03951 | 9/20 | 0.51 |
| ▸ | PLG | P00747 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | F7 | P08709 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672984 | 1.00 | CFD (0.67) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29672975 | 0.92 | CFD (0.66) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23217524 | 0.92 | CFD (0.66) | CFDTPSB2F11PLGPLAU | |
| Hydrochloric Acid SCHEMBL31026073 | 0.91 | CFD (0.65) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL30010372 | 0.90 | CFD (0.55) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23217669 | 0.90 | CFD (0.55) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL21438828 | 0.86 | CFD (0.77) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23217639 | 0.85 | CFD (0.73) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL21437705 | 0.85 | CFD (0.75) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL21455105 | 0.85 | CFD (0.75) | CFDTPSB2F11PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555570-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |