Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 11/20 | 0.45 |
| ▸ | BAX | Q07812 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217873 | 1.00 | CFD (0.45) | CFDBAXALDH1A1PKMMAPT | |
| SCHEMBL28943913 | 0.93 | CFD (0.46) | CFDBAXALDH1A1PKMMAPT | |
| SCHEMBL23217871 | 0.89 | CFD (0.42) | CFDALDH1A1PKMMAPTCYP2C9 | |
| SCHEMBL23217872 | 0.89 | CFD (0.42) | CFDALDH1A1PKMMAPTCYP2C9 | |
| SCHEMBL23217875 | 0.87 | CFD (0.45) | CFDBAXALDH1A1PKMMAPT | |
| SCHEMBL29672942 | 0.87 | CFD (0.53) | CFDBAXALDH1A1PKMMAPT | |
| SCHEMBL30010424 | 0.87 | CFD (0.53) | CFDBAXALDH1A1PKMMAPT | |
| SCHEMBL23217192 | 0.87 | CFD (0.53) | CFDBAXALDH1A1PKMMAPT | |
| SCHEMBL23217894 | 0.86 | CFD (0.51) | CFDTBXAS1 | |
| SCHEMBL23217893 | 0.86 | CFD (0.51) | CFDTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |