SCHEMBL232179

SCHEMBL232179

Fc1ncc(Cl)cc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31514804 1.00
Trifluoromethanesulfonic Acid SCHEMBL7570606 0.81 LMNA (0.41)
SCHEMBL47044 0.79
SCHEMBL781371 0.79
SCHEMBL29386935 0.79
SCHEMBL29374623 0.79
SCHEMBL635255 0.75
SCHEMBL16083962 0.75
SCHEMBL9118637 0.75
SCHEMBL440236 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108069994-B A kind of boron-containing compound and its application in catalytic fluorination reaction 江苏中旗科技股份有限公司 2019-05-14 CN claimed
CN-108069994-A A kind of boron-containing compound and its application in catalytic fluorination reaction 江苏中旗科技股份有限公司 2018-05-25 CN claimed
CN-1830963-A Method for synthesizing 2,3-difluoro-5-chloropyridine WENZHOU NORMAL COLLEGE (CN) 2006-09-13 CN claimed
EP-0710649-B1 Process for the preparation of 2,3-difluoro-5-halopyridines SYNGENTA PARTICIPATIONS AG (CH) 2001-09-05 EP claimed
EP-0556737-B1 Process for the preparation of substituted 2,3-difluoro-pyridines CLARIANT GMBH (DE) 2000-01-12 EP claimed
US-5650517-A Process for the preparation of 2,3-difluoro-5-halopyridines CIBA-GEIGY CORPORATION (US) 1997-07-22 US claimed
EP-0710649-A1 Process for the preparation of 2,3-difluoro-5-halopyridines CIBA-GEIGY AG (CH) 1996-05-08 EP claimed
US-5468863-A Process for the preparation of substituted 2,3-difluoropyridines HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-21 US claimed
EP-0556737-A1 Process for the preparation of substituted 2,3-difluoro-pyridines HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-25 EP claimed
US-12606541-B2 PPARg modulators and methods of use EISAI R&D MANAGEMENT CO., LTD. (JP) 2026-04-21 US disclosed
EP-4539838-A1 NON-ACID INHIBITORS OF INOSITOL HEXAKISPHOSPHATE KINASE (IP6K) AND METHODS OF USE THEREOF Lieber Institute, Inc. (US) 2025-04-23 EP disclosed
US-12268675-B2 Diaryl substituted 6,5-fused ring compounds as C5aR inhibitors CHEMOCENTRYX, INC. (US) 2025-04-08 US disclosed
CN-111788185-B Diaryl substituted 6,5 fused ring compounds as C5a inhibitors 凯莫森特里克斯股份有限公司 2024-12-13 CN disclosed
CN-118946556-A DGK targeting compounds and uses thereof 阿维纳斯运营公司 2024-11-12 CN disclosed
US-4626275-A Certain 5-(pyridyl-2'-oxy)-2-nitrobenzoic acid ester derivatives herbicidal compositions containing same and their herbicidal use CIBA-GEIGY CORPORATION (US) 1986-12-02 US disclosed
EP-0024259-B1 DERIVATIVES OF 5-(PYRIDYL-2-OXY)-2-NITROBENZOIC ACID, THEIR PREPARATION AND HERBICIDAL COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1985-07-31 EP disclosed
EP-0146924-A2 Preparation of difluorpyridine compounds THE DOW CHEMICAL COMPANY (US) 1985-07-03 EP disclosed
US-4420328-A Derivatives of 5-(pyridyl-2-oxy)-2-nitrobenzoic acid, and herbicidal compositions containing them CIBA-GEIGY CORPORATION (US) 1983-12-13 US disclosed
US-4326880-A HERBICIDE CIBA-GEIGY CORPORATION (US) 1982-04-27 US disclosed
EP-0024259-A1 Derivatives of 5-(pyridyl-2-oxy)-2-nitrobenzoic acid, their preparation and herbicidal compositions containing them CIBA-GEIGY AG (CH) 1981-02-25 EP disclosed