Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218653 | 0.94 | TBXAS1 (0.39) | TBXAS1CA12CA9MAPTTSHR | |
| SCHEMBL29853101 | 0.94 | TBXAS1 (0.39) | TBXAS1CA12CA9MAPTTSHR | |
| SCHEMBL29853270 | 0.93 | TBXAS1 (0.39) | TBXAS1CA12CA9MAPTTSHR | |
| SCHEMBL29591417 | 0.93 | TBXAS1 (0.39) | TBXAS1CA12CA9MAPTTSHR | |
| SCHEMBL23218810 | 0.93 | TBXAS1 (0.39) | TBXAS1CA12CA9MAPTTSHR | |
| SCHEMBL23218330 | 0.92 | TBXAS1 (0.40) | TBXAS1CA12CA9MAPTTSHR | |
| SCHEMBL29853121 | 0.91 | TBXAS1 (0.39) | TBXAS1CA12CA9MAPTTSHR | |
| SCHEMBL23218582 | 0.91 | TBXAS1 (0.39) | TBXAS1CA12CA9MAPTTSHR | |
| SCHEMBL23218141 | 0.88 | TSHR (0.39) | CA12CA9MAPTTSHRMTNR1A | |
| SCHEMBL23219259 | 0.88 | TBXAS1 (0.41) | TBXAS1CA12CA9MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |