Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 6/20 | 0.51 |
| ▸ | PLG | P00747 | 3/20 | 0.51 |
| ▸ | PLAU | P00749 | 3/20 | 0.51 |
| ▸ | F11 | P03951 | 3/20 | 0.51 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.40 |
| ▸ | METTL14 | Q9HCE5 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29592855 | 1.00 | CFD (0.51) | CFDPLGPLAUF11TPSB2 | |
| SCHEMBL23218306 | 0.89 | CFD (0.46) | CFDPLGPLAUF11TPSB2 | |
| SCHEMBL29852729 | 0.89 | CFD (0.46) | CFDPLGPLAUF11TPSB2 | |
| SCHEMBL29592336 | 0.87 | CFD (0.70) | CFDPLGPLAUF11TPSB2 | |
| SCHEMBL23218477 | 0.87 | CFD (0.70) | CFDPLGPLAUF11TPSB2 | |
| SCHEMBL23218314 | 0.85 | CFD (0.56) | CFDPLGPLAUF11TPSB2 | |
| SCHEMBL29593126 | 0.85 | CFD (0.56) | CFDPLGPLAUF11TPSB2 | |
| SCHEMBL23218745 | 0.85 | CFD (0.52) | CFDPLGPLAUF11TPSB2 | |
| SCHEMBL29593276 | 0.85 | CFD (0.52) | CFDPLGPLAUF11TPSB2 | |
| SCHEMBL23218034 | 0.83 | CFD (0.58) | CFDPLGPLAUF11TPSB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12558341-B2 | Oral complement factor D inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20250186391-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2025-06-12 | — | — | US | disclosed |
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12558341-B2 | Oral complement factor D inhibitors | CFD, CFH, CFB | CFD 1/4885PLG 421/4885PLAU 1119/4885 |
| US-20250186391-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | CFD, CFH, CFB | CFD 1/4885PLG 89/4885PLAU 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.