Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23228979 | 0.88 | KDM4E (0.42) | SCN9AMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL28736179 | 0.88 | KDM4E (0.42) | SCN9AMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL29852626 | 0.88 | KDM4E (0.42) | SCN9AMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL23218963 | 0.82 | SCN9A (0.36) | SCN9AMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL29593217 | 0.82 | SCN9A (0.36) | SCN9AMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL23218966 | 0.82 | SCN9A (0.36) | SCN9AMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL28736230 | 0.77 | CCR5 (0.40) | MEN1KMT2ALMNA | |
| SCHEMBL1505058 | 0.72 | PTGER1 (0.57) | SCN9ATSHRCNR2PTGER1 | |
| SCHEMBL23218566 | 0.72 | MAPT (0.38) | MEN1CYP1A2CYP2C19KMT2AIRAK4 | |
| SCHEMBL23218564 | 0.72 | MAPT (0.38) | MEN1CYP1A2CYP2C19KMT2AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |