Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29592513 | 1.00 | HTR2A (0.33) | HTR2AHTR2CHTR2BPTPN1 | |
| SCHEMBL23219223 | 0.88 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL29591185 | 0.88 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL23218517 | 0.76 | KCNA3 (0.35) | HTR2AHTR2CHTR2BPTPN1 | |
| SCHEMBL29591905 | 0.76 | KCNA3 (0.35) | HTR2AHTR2CHTR2BPTPN1 | |
| SCHEMBL23218372 | 0.76 | SIRT2 (0.35) | PTPN1 | |
| SCHEMBL23219171 | 0.75 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL29591406 | 0.74 | — | — | |
| SCHEMBL23219152 | 0.74 | — | — | |
| SCHEMBL19683573 | 0.73 | HTR2A (0.38) | HTR2AHTR2CHTR2BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |