Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 6/20 | 0.51 |
| ▸ | F11 | P03951 | 2/20 | 0.40 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852740 | 0.84 | CFD (0.50) | CFDF11TPSB2FFAR1MTNR1A | |
| SCHEMBL23218206 | 0.84 | CFD (0.50) | CFDF11TPSB2FFAR1MTNR1A | |
| SCHEMBL29852668 | 0.77 | CFD (0.45) | CFDF11TPSB2SUCNR1FFAR1 | |
| SCHEMBL23218403 | 0.77 | CFD (0.45) | CFDF11TPSB2SUCNR1FFAR1 | |
| SCHEMBL28736109 | 0.76 | CFD (0.44) | CFDF11TPSB2SUCNR1FFAR1 | |
| SCHEMBL29853127 | 0.76 | CFD (0.44) | CFDF11TPSB2SUCNR1FFAR1 | |
| SCHEMBL23218518 | 0.74 | CFD (0.61) | CFDF11TPSB2FFAR1PLG | |
| SCHEMBL29591826 | 0.74 | CFD (0.61) | CFDF11TPSB2FFAR1PLG | |
| SCHEMBL23218306 | 0.73 | CFD (0.46) | CFDF11TPSB2LOXL2RAB9A | |
| SCHEMBL29852729 | 0.73 | CFD (0.46) | CFDF11TPSB2LOXL2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |