Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 5/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2510637 | 1.00 | ALDH1A1 (0.34) | ALDH1A1MAPTPKMHPGDALOX15 | |
| SCHEMBL2510638 | 1.00 | ALDH1A1 (0.34) | ALDH1A1MAPTPKMHPGDALOX15 | |
| SCHEMBL2321882 | 1.00 | ALDH1A1 (0.34) | ALDH1A1MAPTPKMHPGDALOX15 | |
| SCHEMBL20040523 | 0.82 | TDP1 (0.35) | ALDH1A1MAPT | |
| SCHEMBL12197563 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTPKMHPGDALOX15 | |
| SCHEMBL2507611 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL2507608 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL15320020 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL2511662 | 0.74 | CDC25A (0.34) | ALDH1A1CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL2511661 | 0.74 | CDC25A (0.34) | ALDH1A1CYP2C19CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534140-B1 | EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS | TRUSTEES BOSTON COLLEGE (US) | 2018-04-11 | — | — | EP | disclosed |
| US-8598400-B2 | Efficient methods for Z- or cis-selective cross-metathesis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-12-03 | — | — | US | disclosed |
| US-8552242-B2 | — | — | 2013-10-08 | — | — | US | disclosed |
| EP-2534140-A1 | EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS | Trustees of Boston College (US) | 2012-12-19 | — | — | EP | disclosed |
| US-20110245477-A1 | EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS | TRUSTEES OF BOSTON COLLEGE (US) | 2011-10-06 | — | — | US | disclosed |
| WO-2011097642-A1 | EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS | TRUSTEES OF BOSTON COLLEGE (US) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245477-A1 | EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS | PAICS, COASY, CYP51A1 | ALDH1A1 701/4885MAPT 4607/4885PKM 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.