SCHEMBL232190

SCHEMBL232190

c1nc(C2CC2)c[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17604203 0.91 HRH4 (0.36)
SCHEMBL7672211 0.89 ESR2 (0.35)
SCHEMBL8130205 0.87
SCHEMBL3308039 0.87 HRH4 (0.42)
Hydrochloric Acid SCHEMBL949115 0.85 HRH4 (0.41)
Hydrochloric Acid SCHEMBL9134652 0.85 HRH4 (0.41)
SCHEMBL8017350 0.83 HTR1D (0.38)
Hydrochloric Acid SCHEMBL22227905 0.82 HTR1D (0.37)
Hydrochloric Acid SCHEMBL22228060 0.82 HTR1D (0.37)
SCHEMBL27034282 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138969-A1 TRIAZOLE COMPOUND HAVING NOVEL RING STRUCTURE, METHOD FOR PREPARING SAME, AND USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-05-21 US claimed
EP-4745133-A1 TRIAZOLE COMPOUND HAVING NOVEL RING STRUCTURE, METHOD FOR PREPARING SAME, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2026-05-20 EP claimed
EP-4276095-A2 PROCESSES FOR PREPARING ASK1 INHIBITORS Gilead Sciences, Inc. (US) 2023-11-15 EP claimed
US-20260138969-A1 TRIAZOLE COMPOUND HAVING NOVEL RING STRUCTURE, METHOD FOR PREPARING SAME, AND USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-05-21 US disclosed
EP-4745133-A1 TRIAZOLE COMPOUND HAVING NOVEL RING STRUCTURE, METHOD FOR PREPARING SAME, AND USE THEREOF Korea Research Institute of Chemical Technology (KR) 2026-05-20 EP disclosed
US-20260132147-A1 BAX INHIBITORS AND USES THEREOF CASE WESTERN RESERVE UNIV (US) 2026-05-14 US disclosed
US-12600719-B2 Salt inducible kinase inhibitors THE GENERAL HOSPITAL CORPORATION (US) 2026-04-14 US disclosed
US-20260060961-A1 SUBSTITUTED HETEROCYCLES AS RAS INHIBITORS JAZZ PHARMACEUTICALS IRELAND LTD (IE) 2026-03-05 US disclosed
US-12552777-B2 Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof ENANTA PHARMACEUTICALS, INC. (US) 2026-02-17 US disclosed
EP-4685141-A1 ISOINDOLINE DERIVATIVE, BENZOINDOLE DERIVATIVE AND USE THEREOF Shanghai Helioson Pharmaceutical Co., Ltd. (CN) 2026-01-28 EP disclosed
EP-4660192-A1 SALT INDUCIBLE KINASE INHIBITORS The General Hospital Corporation (US) 2025-12-10 EP disclosed
CN-101048406-A Novel substituted imidazole derivatives BANYU PHARMA CO LTD (JP) 2007-10-03 CN disclosed
US-20040006120-A1 Use of histamine h3 receptor inverse agonists for the control of appetite and treatment of obesity YATES STEPHEN L (US) 2004-01-08 US disclosed
EP-1320364-A1 THE USE OF HISTAMINE H3-RECEPTOR INVERSE AGONISTS FOR THE CONTROL OF APPETITE AND TREATMENT OF OBESITY GLIATECH, INC. (US) 2003-06-25 EP disclosed
US-20030069295-A1 Use of histamine H3 receptor inverse agonists for the control of appetite and treatment of obesity GLIATECH, INC. 2003-04-10 US disclosed
WO-2002015905-A1 THE USE OF HISTAMINE H3 RECEPTOR INVERSE AGONISTS FOR THE CONTROL OF APPETITE AND TREATMENT OF OBESITY GLIATECH, INC. (US) 2002-02-28 WO disclosed
EP-0837679-B1 2-(1H-4(5)-IMIDAZOYL) CYCLOPROPYL DERIVATIVES GLIATECH INC (US) 2001-10-24 EP disclosed
US-6008240-A AN ANTAGONIST OF HISTAMINE H3 RECEPTORS; FOR TREATING ALLERGY, INFLAMMATION, CARDIOVASCULAR DISEASE (HYPER OR HYPOTENSION), GASTROINTESTINAL DISORDERS, CNS DISORDERS INVOLVING ATTENTION OR COGNITIVE DISORDERS GLIATECH, INC. (US) 1999-12-28 US disclosed
US-5990317-A HISTAMINE H3 RECEPTOR ANTAGONIST FOR TREATING CNS DISORDERS INVOLVING ATTENTION OR COGNITIVE DISORDERS GLIATECH, INC. (US) 1999-11-23 US disclosed
US-5652258-A HISTAMINE ANTAGONISTS GLIATECH, INC. (US) 1997-07-29 US disclosed