⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232190 | 0.87 | — | — | |
| SCHEMBL17604203 | 0.83 | HRH4 (0.36) | — | |
| SCHEMBL3308039 | 0.79 | HRH4 (0.42) | — | |
| Hydrochloric Acid SCHEMBL9134652 | 0.78 | HRH4 (0.41) | — | |
| Hydrochloric Acid SCHEMBL949115 | 0.78 | HRH4 (0.41) | — | |
| SCHEMBL7672211 | 0.78 | ESR2 (0.35) | — | |
| SCHEMBL8017350 | 0.76 | HTR1D (0.38) | — | |
| SCHEMBL27034282 | 0.74 | — | — | |
| SCHEMBL14330870 | 0.73 | DHFR (0.35) | — | |
| SCHEMBL8508488 | 0.72 | HTR3A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991639-A1 | 4- (1H-IMIDAZOL-4-YL)PIPERIDIN-1-YL]ANILIDE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPY | SANOFI-SYNTHELABO (FR) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000379-A1 | 4-[(1H-IMIDAZOL-4-YL)PIPERIDIN-1-YL]ANILIDE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPY | SANOFI-SYNTHELABO (FR) | 1999-01-07 | — | — | WO | disclosed |