Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 17/20 | 0.51 |
| ▸ | F11 | P03951 | 9/20 | 0.49 |
| ▸ | TPSB2 | P20231 | 7/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.49 |
| ▸ | PLAU | P00749 | 3/20 | 0.49 |
| ▸ | PLG | P00747 | 2/20 | 0.49 |
| ▸ | F7 | P08709 | 2/20 | 0.49 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852831 | 1.00 | CFD (0.51) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23218616 | 0.94 | CFD (0.51) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL29853351 | 0.94 | CFD (0.51) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL29852644 | 0.92 | CFD (0.51) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23218187 | 0.92 | CFD (0.51) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23218156 | 0.91 | CFD (0.48) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL29852661 | 0.91 | CFD (0.48) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23218837 | 0.90 | CFD (0.53) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23218075 | 0.90 | CFD (0.63) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL29852712 | 0.90 | CFD (0.53) | CFDF11TPSB2KLKB1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |