Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 15/20 | 0.50 |
| ▸ | F11 | P03951 | 7/20 | 0.48 |
| ▸ | TPSB2 | P20231 | 6/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852619 | 0.94 | CFD (0.51) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23219099 | 0.94 | CFD (0.51) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL29852901 | 0.94 | CFD (0.51) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23218554 | 0.94 | CFD (0.51) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL29853050 | 0.93 | CFD (0.52) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23218870 | 0.93 | CFD (0.52) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL29853021 | 0.92 | CFD (0.49) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23218065 | 0.92 | CFD (0.49) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23219139 | 0.90 | CFD (0.41) | CFDF11TPSB2KLKB1PLAU | |
| SCHEMBL23218078 | 0.89 | CFD (0.63) | CFDF11TPSB2KLKB1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |