Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 19/20 | 0.50 |
| ▸ | TPSB2 | P20231 | 4/20 | 0.46 |
| ▸ | F11 | P03951 | 3/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29591368 | 1.00 | CFD (0.50) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29853039 | 1.00 | CFD (0.50) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29592655 | 0.93 | CFD (0.46) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29852741 | 0.93 | CFD (0.46) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23219230 | 0.93 | CFD (0.46) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23218079 | 0.91 | CFD (0.52) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29852554 | 0.91 | CFD (0.52) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL23229186 | 0.90 | CFD (0.43) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29591896 | 0.90 | CFD (0.43) | CFDTPSB2F11PLGPLAU | |
| SCHEMBL29852439 | 0.90 | CFD (0.43) | CFDTPSB2F11PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |