SCHEMBL2321947

SCHEMBL2321947

CCOC(=O)C(CC(C)C)(CC(C)C)C(=O)C(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.53
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP4F2 P78329 3/20 0.36
CYP4A11 Q02928 3/20 0.36
PKM P14618 3/20 0.34
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 1/20 0.33
TSHR P16473 2/20 0.33
CYP1A2 P05177 2/20 0.33
ABCB11 O95342 1/20 0.33
CYP3A4 P08684 1/20 0.33
HTR2A P28223 1/20 0.33
PMP22 Q01453 1/20 0.33
PPARA Q07869 1/20 0.33
THRB P10828 1/20 0.33
LMNA P02545 2/20 0.32
HSD17B10 Q99714 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2316479 0.87 MMP8 (0.45) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL234014 0.86 MMP8 (0.56) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL9052824 0.82 MMP8 (0.53) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL13020677 0.82 MMP8 (0.50) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL9364104 0.81 MMP8 (0.51) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL2319226 0.81 MMP8 (0.51) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL27724022 0.81 MMP8 (0.51) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL2319257 0.80 MEN1 (0.46) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL28137704 0.79 MMP8 (0.50) MMP8MEN1KMT2ACYP4F2CYP4A11
SCHEMBL7781952 0.79 MMP8 (0.50) MMP8MEN1KMT2ACYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1730204-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SRL (IT) 2011-08-10 EP disclosed
US-7544748-B2 Components and catalysis for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2009-06-09 US disclosed
US-20070208150-A1 Components and Catalysis for the Polymerization of Olefins BASELL POLIOLEFINE ITALIA S.R.L (IT) 2007-09-06 US disclosed
EP-1730204-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2006-12-13 EP disclosed
WO-2005097841-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2005-10-20 WO disclosed