Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20414770 | 0.93 | GAA (0.39) | GAANR1I2TLR8TP53 | |
| SCHEMBL20633873 | 0.93 | GAA (0.39) | GAANR1I2TLR8TP53 | |
| SCHEMBL19544072 | 0.93 | GAA (0.39) | GAANR1I2TLR8TP53 | |
| SCHEMBL19237046 | 0.93 | GAA (0.39) | GAANR1I2TLR8TP53 | |
| SCHEMBL26787995 | 0.92 | GAA (0.38) | GAATLR8TP53 | |
| SCHEMBL23172216 | 0.92 | GAA (0.38) | GAATLR8TP53 | |
| SCHEMBL22350121 | 0.90 | GAA (0.37) | GAATLR8TP53 | |
| SCHEMBL25960091 | 0.84 | NR1I2 (0.33) | NR1I2 | |
| SCHEMBL22597187 | 0.81 | GAA (0.38) | GAATLR8TP53 | |
| SCHEMBL23082899 | 0.81 | GAA (0.38) | GAATLR8TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975088-B2 | Imidazo[2,1-f][1,2,4]triazine compounds as pi3k-y inhibitors | INCYTE CORPORATION (US) | 2021-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975088-B2 | Imidazo[2,1-f][1,2,4]triazine compounds as pi3k-y inhibitors | PIK3R5, PIK3CD, PIK3CA | GAA 1236/4885NR1I2 729/4885TLR8 3216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.