Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17139562 | 0.88 | PTGS1 (0.49) | PTGS1PTGS2MAPK1 | |
| SCHEMBL18666813 | 0.82 | PTGS1 (0.41) | PTGS1PTGS2MAPK1 | |
| SCHEMBL19777418 | 0.77 | MGLL (0.38) | PTGS1PTGS2MAPK1 | |
| SCHEMBL21179865 | 0.77 | MGLL (0.38) | PTGS1PTGS2MAPK1 | |
| SCHEMBL20763212 | 0.76 | PTGS1 (0.34) | PTGS1PTGS2 | |
| SCHEMBL17148101 | 0.76 | PTGS1 (0.36) | PTGS1PTGS2MAPK1 | |
| SCHEMBL17325350 | 0.73 | PTGS1 (0.41) | PTGS1PTGS2MAPK1 | |
| SCHEMBL17953261 | 0.73 | PTGS1 (0.41) | PTGS1PTGS2MAPK1 | |
| SCHEMBL17151032 | 0.73 | PTGS1 (0.47) | PTGS1PTGS2MAPK1 | |
| SCHEMBL17151147 | 0.73 | PTGS1 (0.44) | PTGS1PTGS2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975112-B2 | Linkers for conjugation of cell-binding molecules | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975112-B2 | Linkers for conjugation of cell-binding molecules | EPCAM, CD44, CD2BP2 | PTGS1 3986/4885PTGS2 4053/4885MAPK1 4382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.