⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19766555 | 0.78 | — | — | |
| SCHEMBL19766566 | 0.71 | — | — | |
| SCHEMBL23488099 | 0.69 | DNM1 (0.31) | — | |
| SCHEMBL19087025 | 0.68 | — | — | |
| SCHEMBL19116496 | 0.67 | SLC6A2 (0.31) | — | |
| SCHEMBL15183670 | 0.65 | — | — | |
| SCHEMBL22967532 | 0.65 | KDM1A (0.37) | — | |
| SCHEMBL19077898 | 0.63 | — | — | |
| SCHEMBL23282418 | 0.61 | ASGR1 (0.40) | — | |
| SCHEMBL10228721 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975088-B2 | Imidazo[2,1-f][1,2,4]triazine compounds as pi3k-y inhibitors | INCYTE CORPORATION (US) | 2021-04-13 | — | — | US | disclosed |