⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22272039 | 0.65 | — | — | |
| SCHEMBL1276874 | 0.65 | — | — | |
| SCHEMBL26083942 | 0.65 | — | — | |
| SCHEMBL22328087 | 0.65 | — | — | |
| SCHEMBL29013140 | 0.65 | — | — | |
| SCHEMBL24172460 | 0.65 | — | — | |
| SCHEMBL178547 | 0.65 | — | — | |
| Bromide SCHEMBL5086817 | 0.62 | — | — | |
| SCHEMBL29666349 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL5086872 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139478-A1 | OCTAHYDRO FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS | CORCEPT THERAPEUTICS, INC. | 2021-05-13 | — | — | US | disclosed |
| US-10973813-B2 | Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators | CORCEPT THERAPEUTICS, INC. (US) | 2021-04-13 | — | — | US | disclosed |