SCHEMBL23221900

SCHEMBL23221900

CCCCNCCOCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TSHR P16473 3/20 0.50
CYP2C19 P33261 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
KDM4E B2RXH2 6/20 0.39
POLB P06746 1/20 0.39
THRB P10828 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
GLA P06280 1/20 0.38
ADH1B P00325 1/20 0.37
ADH1C P00326 1/20 0.37
ADH1A P07327 1/20 0.37
ADH7 P40394 1/20 0.37
ACHE P22303 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17254501 0.93 TSHR (0.62) ALDH1A1TSHRCYP2C19CYP1A2KDM4E
SCHEMBL12321612 0.91 TSHR (0.59) ALDH1A1TSHRCYP2C19CYP1A2KDM4E
SCHEMBL7139396 0.87 ALDH1A1 (0.54) ALDH1A1TSHRCYP2C19CYP1A2CYP3A4
SCHEMBL239490 0.87 ALDH1A1 (0.45) ALDH1A1TSHRCYP2C19CYP1A2KDM4E
SCHEMBL15782518 0.85 TSHR (0.51) ALDH1A1TSHRCYP2C19CYP1A2CYP3A4
SCHEMBL11726100 0.85 TSHR (0.50) ALDH1A1TSHRCYP2C19CYP1A2CYP3A4
SCHEMBL4354624 0.84
Hydrochloric Acid SCHEMBL1965268 0.84 ALDH1A1 (0.43) ALDH1A1TSHRCYP2C19CYP1A2KDM4E
SCHEMBL16948551 0.83 KDM4E (0.46) ALDH1A1TSHRCYP2C19KDM4EPOLB
SCHEMBL8979968 0.83 TSHR (0.55) ALDH1A1TSHRCYP2C19CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3805237-A1 SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) 2021-04-14 EP disclosed