Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IL18 | Q14116 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23222498 | 0.90 | CPS1 (0.37) | SCN9ALMNAKDR | |
| SCHEMBL15584523 | 0.90 | SLC22A12 (0.39) | SCN9APARP15PARP10PARP2POLB | |
| SCHEMBL17052788 | 0.79 | CYP19A1 (0.47) | SCN9APARP15PARP10PARP2ALDH1A1 | |
| SCHEMBL29700357 | 0.78 | PARP15 (0.46) | PARP15PARP10PARP2ALDH1A1POLB | |
| SCHEMBL21745760 | 0.78 | PARP15 (0.46) | PARP15PARP10PARP2ALDH1A1POLB | |
| SCHEMBL21745759 | 0.77 | POLB (0.45) | SCN9APARP15PARP10PARP2ALDH1A1 | |
| SCHEMBL14405698 | 0.77 | CYP17A1 (0.47) | SCN9ARAB9A | |
| SCHEMBL29700365 | 0.76 | KDM4E (0.41) | SCN9APARP15PARP10PARP2ALDH1A1 | |
| SCHEMBL15584628 | 0.76 | KDM4E (0.41) | SCN9APARP15PARP10PARP2ALDH1A1 | |
| SCHEMBL18650595 | 0.76 | MAP4K4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3376865-B1 | 4-((6-(2,4-DIFLUOROPHENYL)-1,1-DIFLUORO-2-HYDROXY-3-(1H | DOW AGROSCIENCES LLC (US) | 2021-04-14 | — | — | EP | disclosed |