Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11913027 | 0.94 | CES2 (0.40) | MAP4K4PIK3CAKCNH2MINK1PI4KB | |
| SCHEMBL17120565 | 0.84 | CES2 (0.42) | PTGS2DHODH | |
| SCHEMBL23222498 | 0.84 | CPS1 (0.37) | LOXL2 | |
| SCHEMBL18655752 | 0.79 | CYP3A4 (0.37) | DHODH | |
| SCHEMBL11917195 | 0.78 | CYP3A4 (0.48) | — | |
| SCHEMBL20903514 | 0.78 | GAA (0.40) | — | |
| SCHEMBL17113449 | 0.76 | CYP3A4 (0.50) | — | |
| SCHEMBL23222499 | 0.76 | SCN9A (0.38) | — | |
| SCHEMBL29061268 | 0.75 | CYP3A4 (0.36) | KCNH2 | |
| SCHEMBL18661269 | 0.74 | CES2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000465-B2 | Antifungal compound process | Mycovia Pharmaceuticals, Inc. (US) | 2018-06-19 | — | — | US | disclosed |
| US-9981943-B2 | Antifungal compound process | Mycovia Pharmaceuticals, Inc. (US) | 2018-05-29 | — | — | US | disclosed |
| US-9802914-B2 | Antifungal compound process | VIAMET PHARMACEUTICALS, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-20170144990-A1 | ANTIFUNGAL COMPOUND PROCESS | Mycovia Pharmaceuticals, Inc. | 2017-05-25 | — | — | US | disclosed |
| US-20170144991-A1 | ANTIFUNGAL COMPOUND PROCESS | Mycovia Pharmaceuticals, Inc. | 2017-05-25 | — | — | US | disclosed |
| US-20170088539-A1 | ANTIFUNGAL COMPOUND PROCESS | Mycovia Pharmaceuticals, Inc. | 2017-03-30 | — | — | US | disclosed |
| US-20170088540-A1 | ANTIFUNGAL COMPOUND PROCESS | Mycovia Pharmaceuticals, Inc. | 2017-03-30 | — | — | US | disclosed |
| US-20170081309-A1 | ANTIFUNGAL COMPOUND PROCESS | Mycovia Pharmaceuticals, Inc. | 2017-03-23 | — | — | US | disclosed |
| US-20170081310-A1 | ANTIFUNGAL COMPOUND PROCESS | Mycovia Pharmaceuticals, Inc. | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000465-B2 | Antifungal compound process | ERG28, DPM1, CYP51A1 | MAP4K4 2226/4885PIK3CA 922/4885KCNH2 2433/4885 |
| US-20170144991-A1 | ANTIFUNGAL COMPOUND PROCESS | ERG28, DPM1, CYP51A1 | MAP4K4 2226/4885PIK3CA 922/4885KCNH2 2433/4885 |
| US-20170144990-A1 | ANTIFUNGAL COMPOUND PROCESS | ERG28, DPM1, CYP51A1 | MAP4K4 2226/4885PIK3CA 922/4885KCNH2 2433/4885 |
| US-20170088540-A1 | ANTIFUNGAL COMPOUND PROCESS | ERG28, DPM1, CYP51A1 | MAP4K4 2226/4885PIK3CA 922/4885KCNH2 2433/4885 |
| US-20170081310-A1 | ANTIFUNGAL COMPOUND PROCESS | ERG28, DPM1, CYP51A1 | MAP4K4 2226/4885PIK3CA 922/4885KCNH2 2433/4885 |
| US-20170088539-A1 | ANTIFUNGAL COMPOUND PROCESS | ERG28, DPM1, CYP51A1 | MAP4K4 2226/4885PIK3CA 922/4885KCNH2 2433/4885 |
| US-20170081309-A1 | ANTIFUNGAL COMPOUND PROCESS | ERG28, DPM1, CYP51A1 | MAP4K4 2209/4885PIK3CA 900/4885KCNH2 2419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.