Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 4/20 | 0.47 |
| ▸ | IL2 | P60568 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226707 | 0.91 | STING1 (0.47) | STING1IL2CA12CA1CA2 | |
| SCHEMBL23226421 | 0.91 | STING1 (0.47) | STING1KIF11IL2CA12CA1 | |
| SCHEMBL23226430 | 0.89 | STING1 (0.46) | STING1KIF11IL2CA12CA1 | |
| SCHEMBL23226588 | 0.89 | STING1 (0.45) | STING1IL2CA12CA1CA2 | |
| SCHEMBL23226716 | 0.88 | STING1 (0.63) | STING1MEN1KMT2ALMNAMAPT | |
| SCHEMBL23212313 | 0.87 | KIF11 (0.60) | STING1KIF11CA1CA2MEN1 | |
| SCHEMBL30116577 | 0.87 | KIF11 (0.60) | STING1KIF11CA1CA2MEN1 | |
| SCHEMBL23212314 | 0.87 | STING1 (0.67) | STING1CA12CA1CA2CA9 | |
| SCHEMBL23226475 | 0.87 | MEN1 (0.46) | STING1IL2CA12CA1CA2 | |
| SCHEMBL23226621 | 0.86 | STING1 (0.45) | STING1IL2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409223-B | Amide compound and medical application thereof as STING inhibitor | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |
| WO-2021068950-A1 | AMIDE COMPOUND AND MEDICAL USE THEREOF AS STING INHIBITOR | 中国药科大学 | 2021-04-15 | — | — | WO | disclosed |
| CN-112409223-A | Amide compounds and medical application thereof as STING inhibitor | 中国药科大学 | 2021-02-26 | — | — | CN | disclosed |