Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PPM1B | O75688 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25714044 | 0.86 | CDA (0.42) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 | |
| SCHEMBL21901828 | 0.79 | POLB (0.42) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 | |
| SCHEMBL23227183 | 0.79 | POLB (0.42) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 | |
| SCHEMBL12993288 | 0.78 | NPC1 (0.46) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 | |
| SCHEMBL23227164 | 0.76 | CDA (0.46) | — | |
| SCHEMBL23227162 | 0.76 | CDA (0.46) | — | |
| SCHEMBL12993213 | 0.74 | NPC1 (0.45) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 | |
| SCHEMBL20756600 | 0.73 | DNMT1 (0.38) | NPC1PPM1BPOLBALDH1A1 | |
| SCHEMBL20756152 | 0.73 | NPC1 (0.44) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 | |
| SCHEMBL28422967 | 0.73 | NPC1 (0.44) | CHRNB2CHRNA5CHRNA7CHRNA4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021071890-A1 | 2'-DEOXY-2',2'-DIFLUOROTETRAHYDROURIDINES WITH HIGH PURITY AND METHODS OF MAKING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-04-15 | — | — | WO | disclosed |