Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23227476 | 0.83 | — | — | |
| SCHEMBL23239754 | 0.67 | PLAT (0.40) | PLG | |
| SCHEMBL23215011 | 0.66 | HTR2A (0.35) | — | |
| SCHEMBL29886161 | 0.66 | HTR2A (0.35) | — | |
| SCHEMBL23214880 | 0.66 | HTR2A (0.35) | — | |
| SCHEMBL24945827 | 0.66 | HTR2A (0.35) | — | |
| SCHEMBL23214986 | 0.60 | TRPM5 (0.35) | PLG | |
| SCHEMBL24946305 | 0.60 | TRPM5 (0.35) | PLG | |
| SCHEMBL29886068 | 0.60 | TRPM5 (0.35) | PLG | |
| SCHEMBL29886270 | 0.60 | TRPM5 (0.35) | PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021071832-A1 | ARYL HETEROBICYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS | D.E. SHAW RESEARCH, LLC (US) | 2021-04-15 | — | — | WO | disclosed |