SCHEMBL232280

SCHEMBL232280

CC1(C)CCCC(C)(C)N1.[LiH]

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18074752 0.97 ALDH1A1 (0.31) ALDH1A1
Hydrochloric Acid SCHEMBL23748065 0.97 ALDH1A1 (0.31) ALDH1A1
SCHEMBL15100 0.96 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2
SCHEMBL8303206 0.96 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL21586132 0.94
Hydrochloric Acid SCHEMBL1350259 0.94
Water SCHEMBL14775667 0.93 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL986707 0.93 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2
SCHEMBL10454769 0.93 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2
SCHEMBL14912272 0.93 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2301 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606539-B2 Process for preparation of apalutamide SYNTHON B.V. (NL) 2026-04-21 US claimed
US-20240228480-A1 PROCESSES FOR PREPARING PYRROLOPYRIDINE-ANILINE COMPOUNDS CURIA GLOBAL, INC. 2024-07-11 US claimed
US-20240166597-A1 TOTAL SYNTHESIS METHOD FOR VITAMIN A AND DERIVATIVE THEREOF AND DEUTERATED COMPOUND THEREOF FUDAN UNIVERSITY (CN) 2024-05-23 US claimed
US-11873289-B2 Pyrazole compounds and preparation thereof MyoKardia, Inc. (US) 2024-01-16 US claimed
EP-4289818-A1 TOTAL SYNTHESIS METHOD FOR VITAMIN A, DERIVATIVE AND DEUTERATED COMPOUND THEREOF Fudan University (CN) 2023-12-13 EP claimed
EP-4281069-A1 PROCESSES FOR PREPARING PYRROLOPYRIDINE-ANILINE COMPOUNDS NFlection Therapeutics, Inc. (US) 2023-11-29 EP claimed
US-20230373932-A1 DIHYDROPYRIMIDIN-2-ONE COMPOUNDS AND MEDICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2023-11-23 US claimed
US-20230312507-A1 IMPROVED PROCESS FOR PREPARATION OF APALUTAMIDE SYNTHON B.V. (NL) 2023-10-05 US claimed
EP-4219511-A1 INTERMEDIATE, PREPARING METHOD THEREOF, AND METHOD OF PREPARING DRUG Heron Neutron Medical Corp. (TW) 2023-08-02 EP claimed
US-20230234973-A1 INTERMEDIATE, PREPARING METHOD THEREOF, AND METHOD OF PREPARING DRUG HERON NEUTRON MEDICAL CORP. (TW) 2023-07-27 US claimed
WO-1986001101-A1 LOW CARIOGENIC SWEETENING AGENTS UNIVERSITY OF ILLINOIS (US) 1986-02-27 WO claimed
EP-0021772-B1 METHOD OF PREPARING 2-OXO- AND 2-UNSUBSTITUTED-HEXAHYDROAZEPINE DERIVATIVES JOHN WYETH & BROTHER LIMITED (GB) 1985-01-02 EP claimed
EP-0045524-B1 22-ARYLSULFONYL-24,25-DIHYDROXYCHOLESTANES AND PROCESS FOR PREPARING THE SAME Chugai Seiyaku Kabushiki Kaisha (JP) 1983-10-19 EP claimed
EP-0078026-A2 Antibiotic synthesis MERCK & CO. INC. (US) 1983-05-04 EP claimed
US-4344888-A 24,25-Dihydroxycholestans and process for preparing the same CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1982-08-17 US claimed
EP-0045524-A1 22-Arylsulfonyl-24,25-dihydroxycholestanes and process for preparing the same Chugai Seiyaku Kabushiki Kaisha (JP) 1982-02-10 EP claimed
EP-0007399-B1 INDOLYLALKYL AMINES, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESS FOR THEIR MANUFACTURE MERCK PATENT GmbH (DE) 1982-01-20 EP claimed
US-4296029-A Process for preparing hexahydroazepine, piperidine and pyrrolidine derivatives JOHN WYETH & BROTHER LIMITED (GB) 1981-10-20 US claimed
EP-0021772-A1 Method of preparing 2-oxo- and 2-unsubstituted-hexahydroazepine derivatives JOHN WYETH & BROTHER LIMITED (GB) 1981-01-07 EP claimed
EP-0007399-A1 Indolylalkyl amines, pharmaceutical preparations containing them and process for their manufacture MERCK PATENT GmbH (DE) 1980-02-06 EP claimed