Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365646 | 1.00 | HCAR2 (0.50) | HCAR2NAPRTTTRTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL7476482 | 0.98 | HCAR2 (0.48) | HCAR2NAPRTTTRTSHRKMT2A | |
| Pyridine SCHEMBL5309182 | 0.89 | HCAR2 (0.46) | HCAR2NAPRTTTRTSHRKMT2A | |
| SCHEMBL29838220 | 0.83 | KMT2A (0.46) | NAPRTKMT2ATDP1MEN1ALDH1A1 | |
| SCHEMBL991416 | 0.83 | KMT2A (0.46) | NAPRTKMT2ATDP1MEN1ALDH1A1 | |
| SCHEMBL3650453 | 0.81 | HCAR2 (0.48) | HCAR2NAPRTTTRTSHRKMT2A | |
| SCHEMBL3517645 | 0.81 | HCAR2 (0.48) | HCAR2NAPRTTTRKMT2AMEN1 | |
| SCHEMBL230989 | 0.81 | KMT2A (0.45) | KMT2ATDP1MEN1ALDH1A1KDM4E | |
| SCHEMBL9696266 | 0.81 | TDP1 (0.46) | KMT2ATDP1MEN1ALDH1A1KDM4E | |
| SCHEMBL199221 | 0.81 | TTR (0.54) | HCAR2NAPRTTTRTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 955 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| CN-113912534-B | Biphenyl heterocyclic compound, synthesis method and application thereof | 江苏科技大学 | 2023-07-25 | — | — | CN | claimed |
| WO-2023083161-A1 | BIPHENYL HETEROCYCLIC COMPOUND, AND SYNTHESIS METHOD THEREFOR AND USE THEREOF | 江苏科技大学 | 2023-05-19 | — | — | WO | claimed |
| CN-113980025-B | Nicotine and indole hybrid compound, and synthesis method and application thereof | 江苏科技大学 | 2023-02-24 | — | — | CN | claimed |
| CN-113880847-B | Cyclotryptamine alkaloid, and synthesis method and application thereof | 江苏科技大学 | 2023-02-03 | — | — | CN | claimed |
| CN-115477645-A | Alvatripopa maleate series impurities and preparation method and application thereof | 湖南先施制药有限公司 | 2022-12-16 | — | — | CN | claimed |
| CN-113943947-B | Composite film electrode for electrochemical reduction of carbon dioxide and preparation method thereof | 浙江工业大学 | 2022-11-15 | — | — | CN | claimed |
| CN-115057854-A | Preparation method of Alvatripopa maleate intermediate | 河北常山生化药业股份有限公司 | 2022-09-16 | — | — | CN | claimed |
| CN-113943947-A | Composite film electrode for electrochemical reduction of carbon dioxide and preparation method thereof | 浙江工业大学 | 2022-01-18 | — | — | CN | claimed |
| EP-2697208-A1 | 1,3 OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2014-02-19 | — | — | EP | claimed |
| CN-102675196-B | Method for preparing 5,6-chloronicotinic acid from 2,3-dichloro-5-trichlorine picoline (DCTC) short steaming residue | YANCHENG INST TECHNOLOGY | 2014-01-22 | — | — | CN | claimed |
| WO-2012139993-A1 | 1,3 OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-10-18 | — | — | WO | claimed |
| CN-102675196-A | Method for preparing 5,6-chloronicotinic acid from 2,3-dichloro-5-trichlorine picoline (DCTC) short steaming residue | YANCHENG INST TECHNOLOGY | 2012-09-19 | — | — | CN | claimed |
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) | 2012-04-12 | — | — | US | claimed |
| WO-2010118241-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2010-10-14 | — | — | WO | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | HCAR2 4789/4885NAPRT 384/4885TTR 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.